Accutane (Isotretinoin) is one of the most famous and most controversial acne treatments on the market. This drug is often considered to be the “last resort” for people who suffer from acne and have tried everything else. The drug was first introduced in 1982 by the Hoffman-LaRoche pharmaceutical company. This product has been frequently prescribed to people who suffer from acute acne and severe nodular acne. These people have usually tried several topical treatments that have not been successful for them.
Accutane is actually a vitamin A analog. It ranges in dosage from 10mg to 40mg. The drug is very potent and after four or five months of regular use, the person will see a noticeable difference in their acne. Accutane shuts down the oil production of your skin. It forces sebaceous glands to mature. This process begins by testosterone forcing the sebaceous gland to produce different types of oils that line the hair follicle. When the oil production is stabilized, it is no longer able to clog pores. It also prevents too much keratin to be produce and clog the pores. It can take up to two months for you to see a difference. It is recommended that people take Accutane with fatty foods, such as milk. This allows the drug to be easily absorbed.
Accutane does have a number of drawbacks. Users often experience a worsening of symptoms before they see improvement. They may also experience dry skin, lips and eyes. It has also been linked to several birth defects and should not be taken by women who are pregnant. Women may also need to use two types of contraception when on Accutane. It may also cause depression and digestive problems.
Accutane has been pretty successful. About 35-38% of patients will experience complete remission after one course. People with severe, stubborn acne may need more than one course. After one course, 70% of people have experienced remission of symptoms. One course of treatment is usually about four to six months.